Absorption of curcumin
The bioavailability of Cureit is much higher than the bioavailability of standart curcumin. Another important benefit of Cureit is its long duration of action in the body.
As seen from the graph, Cureit curcuminoids persist in blood for hours. This is called a ”therapeutic window” – the wider (longer) it is, the better benefit of the product can be expected.
Cureit is unique for its bioavailability that is much higher than the bioavailability of the other curcumin formulations containing absorption enhancers. As for the time of the occurence in the organism, the other curcumin formulations peak within the first hour and then rapidly drop down, while CureIt curcuminoids persists in blood for hours.
What is bioavailability ?
Bioavailability refers to the extent and rate at which the active drug or metabolite enters systemic circulation, thereby accessing the site of action.
When a medication is administered intravenously, its bioavailability is 100%. However, when a medication is administered via other routes (such as oral), its bioavailability generally decreases (due to the incomplete absorption and first-pass metabolism) or may vary from patient to patient.
Bioavailability is one of the essential tools in pharmacokinetics, as bioavailability must be considered when calculating dosages for non-intravenous routes of administration. Bioavailability of a drug is largely determined by the properties of the dosage form, which depend partly on its design and manufacture. Differences in bioavailability among formulations of a given drug can have clinical significance; thus, knowing whether drug formulations are equivalent is essential.